Systems Neurobiology

How Neural Circuits Generate Eye Movements

As an animal actively navigates, or is passively carried through, its environment, its eyes receive continuous visual motion signals generated by its own movement relative to its stable surroundings. How does the vertebrate brain process such visual information and prepare compensatory locomotor and eye movement behavior?

Our group investigates the underlying neural circuits in live zebrafish larvae. We aim to understand how optic flow is filtered by the optic tectum and the pretectum to generate eye movement behaviors such as the optokinetic response.

Furthermore, we study how local networks produce function in the (pre‑) motor systems in the hindbrain. The neural integrator for horizontal eye movements forms a short-lived memory of eye positions by maintaining eye-position related neural activity in the absence of input.

It serves as a paradigm to identify mechanisms of short-term information storage, which is also needed in many other vertebrate brain areas of higher complexity.

We use a combination of optogenetics, two-photon microscopy, genetics, behavioral assays, as well as other physiological approaches and computation to investigate the architecture and mechanisms of these neural circuits.

Job Opening: Postdoc Position Visual Circuits

Arrenberg lab currently has an opening for a postdoc working on visual circuits. Find full details here, or download the job advert here.

Group Leader and Further Information

Aristides Arrenberg
Systems Neurobiology
Werner Reichardt Centre for Integrative Neuroscience
Otfried-Mueller-Str. 25
72076 Tübingen

Phone: +49 (0)7071 29 88798
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