Today, Nature Neuroscience published the study spearheaded by Alexandra and Katja, with help from Hartwig and Anahit. We show that depending on the ambient light level, the retina changes its "language" with which it talks to the brain. For more information see the press release in German (pdf) or in English (pdf). The study can be found here.
Multi-electrode array recordings are very popular to study the retina. In the past couple of yours, we have developed and perfected the methodology of using perforated MEAs for this purpose, which give exquisite signal-to-noise ratio. We have published a methods paper today with step-by-step instructions to do this, so that other labs can also successfully apply this technique. The technique was predominantly developed by Katja, Alexandra and Hartwig, but most other lab members have contributed to this paper as well.
Reinhard K, Tikidji-Hamburyan A, Seitter H, Idrees S, Mutter M, Benkner B, Münch TA. Step-by-step instructions for retina recordings with perforated multi electrode arrays. PLoS One. 2014 Aug 28;9(8):e106148. doi: 10.1371/journal.pone.0106148. eCollection 2014. PubMed PMID: 25165854; PubMed Central PMCID: PMC4148441.
Boris has characterized the behavior of treated animals in the publication
Carido M, Zhu Y, Postel K, Benkner B, Cimalla P, Karl MO, Kurth T, Paquet-Durand F, Koch E, Münch TA, Tanaka EM, Ader M. Characterization of a Mouse Model With Complete RPE Loss and Its Use for RPE Cell Transplantation. Invest Ophthalmol Vis Sci. 2014 Aug 7;55(8):5431-44. doi: 10.1167/iovs.14-14325. PubMed PMID: 25103259.
We made a strong showing at the FASEB meeting on Retinal Neurobiology and Visual Processing in Saxtons River, VT, USA, June 22-27. With 9 posters and participants, we might have been the lab with most presentations. Alexandra's and Natalia's abstracts have been chosen to be presented in the poster highlights sessions.
Katja, Marion and Alexandra participated at the ARVO (Association for Research in Vision and Ophthalmology) meeting in Orlando, Florida, from May 4 to 8. The ARVO meeting is the largest meeting of its kind. Marion and Katja presented posters on their work with human retina, with Katja receiving a travel grant and a poster award. Alexandra's abstracts have been selected for talks, presented by herself and by me.
Alexandra has submitted two abstracts to the ARVO meeting in Orlando, Florida. Both have been selected to be presented as talks during the meeting, which means that they have received the highest ratings by the program commitee. Congratulations!
Katja Reinhard has been awarded a travel grant to participate at the ARVO meeting 2014 in Orlando, Florida. In addition, her abstract has been selected as one of the 5 best posters and will participate in the "Members in Training" poster competition. Congratulations, Katja!
Today, Saad Idrees joined our lab as a new PhD student. Welcome!
Congratulations to Marion!
Her study on improving optogenetic vision has been published today by PLOS ONE. In this paper, we show how the properties of channelrhodopsin can be adjusted so that optogenetic vision can be feasible over a 100-fold bigger brightness range than with current approaches.
See also: Press release of the University
Congratulations to Katja! Today, she has been given the Lush Prize 2013 in the category "Young Researcher". The Lush Prize honors new developments in the replacement of animal experiments. katja won the prize for establishing in vitro experiments with human retina. The Lush prize comes with a £12.500 bursary.
Welcome back to Nadine! After her time off for maternal leave, Nadine is back in the lab.
Marion has finished her Master, and is now officially a PhD student! Congratulations for her excellent work and magnificent master's thesis!
We have also been visited by Monika Seynsche from Deutschlandfunk, who has produced a radio report about the work:
We are happy that two excellent students are joining our lab today for internships. Tamara Simonyan is joining our lab for 3 months as a DAAD exchange student. Dana Cobb is coming with a Baden-Württemberg stipend to work with us for 6 weeks. Welcome!
Congratulation! Alexandra defended her thesis today, and is now the very first PhD graduate from our laboratory. She is off for a post doc with E.J. Chichilnisky at the Salk Institute in San Diego.
Natalia, Katja, and Hartwig also participated in the Camp, that brought together well over 100 young vision scientists from all over Europe.
Congratulations! Katja won a PhD Fellowship from the Pro-Retina Foundation for her project to investigate visual processing of the human retina in vitro.
The Pro Retina Foundation is a patient-led organization devoted to finding cures for degenerative eye diseases.
Congratulations to Britni Crocker! Her excellent work during her lab rotation has made it into a publication in Neuron. Today, Neuron published our work that we have performed in collaboration with Frank W. Pfrieger from the Institute of Cellular and Integrative Neuroscience (INCI) at the University of Strasbourg.
Marion Mutter has joined our lab today to work on her Master's project. She has already worked for a while with Boris, where she assisted him with behavior experiments. Welcome!
It is quite some work to pack a whole lab, let alone a whole institute... Starting from April 16, 2012, we will be located in our brand new lab building at Ottfried-Müller-Str. 25, right next to the Hertie Institute.
Nadine is taking a leave of absence. Good luck, all the best, and thank you for your great work!
We are very happy that Elli is joining our lab as a technical assistant.
Natalia and Jad joined our lab today. Natalia will do her PhD in our lab, while Jad is starting a 10-week lab rotation as part of his Master's education.
Katja Reinhard started today in our lab to work towards her PhD. Welcome!
18 girls, from 7th to 12th grade, from schools in and around Tübingen, visited our lab today during the Girls' Day 2011. They learned about the tricks of the trade when doing behavioral experiments to asses the quality of vision.
Congratulations to Hartwig and Alexandra!
Hartwig was accepted for the "Paris School of Neuroscience - Spring School 2011" on Optical Imaging and Electrophysiological Recording in Neuroscience from April 12 - April 20.
Alexandra was accepted to the "Okinawa Computational Neuroscience Course 2011" from June 13 - June 30.
The German Research Council today announced their decision on the first round of the next Excellence Initiative. The local Tübingen radio station, SWR4, took this as an opportunity to make a program about the CIN, with information about our lab's work. There is also an interview with the CIN's speaker, Peter Thier (starting at 3:56 in the audio file).
Our laboratory is part of the Tübingen Bernstein Center for Computational Neuroscience.