Prof. Dr. Mathias Jucker

  Name Contact
Prof. Dr. Mathias Jucker Prof. Dr. Mathias Jucker
Email:write Email
Tel.:+49 (0)7071 29 86863
www:website
Adr.:Dept. of Cellular Neurology
Hertie Institute for Clinical Brain Research
Otfried-Müller-Straße 27
 72076 Tübingen
 Germany
Area / Position CIN-Member
Department HIH Cellular Neurology, HIH and DZNE Tübingen
Scientific topic Brain Aging and Alzheimer's Disease
Field of research The research focus of the department is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases with a special focus on the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathies.
Methods Transgenic mouse models; in vivo multiphoton imaging; neuro-stereology
Publications
  1. Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret J, Paganetti P, Walsh DM, Mathews P, Ghiso J, Staufenbiel M, Walker L, Jucker M (2006) Exogenous induction of Afl-amyloidogenesis is governed by intrinsic properties of agent and host. Science. 313(5794):1781-4.
  2. Kaeser SA, Herzig MC, Coomaraswamy J, Kilger E, Selenica MLB, Winkler D, Staufenbiel M, Levy E, Grubb A, Jucker M (2007). Cystatin C modulates cerebral fl-amyloidosis. Nat Genet. 39(12):1437-9.
  3. Grathwohl SA, Kälin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, Jucker M (2009). Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat Neurosci. 2012(11):1361-3.
Keywords brain imaging; glia; neuro-immunology; neuro-pathology; neuro-plasticity; neurodegeneration
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News & Press
April 16 2014
A Profile of Werner Reichardt

A look at Werner Reichardt's career from Max Planck Research.


December 4 2013
No Blue Skies for Mice

Scientists at the University of Tübingen study the differential distribution of photoreceptors in the retina of mice

November 28 2013
A New Computer Simulation for the Treatment of Eye Disease

A new study shows the possibilities and limitations of optogenetics as a treatment strategy for forms of blindness.


November 15 2013
International Prize for CIN PhD Student

Katja Reinhard has been awarded the 2013 Lush Prize for research that holds out the prospect of developing new treatments for blindness.

Next Events

April 24 2014, 6:15pm
Neurocolloquium - Two memory systems in the temporal lobe: hippocampus and amygdala
Children‘s Hospital, Hoppe-Seyler-Str. 1, Lecture Hall, Floor C3
 

April 29 2014, 2:30pm
An Update on Bionic Vision, Australia's Retinal Prosthesis Program
Lecture Room, Forschungsstelle für Experimentelle Ophthalmologie, Röntgenweg 11