Prof. Dr. Mathias Jucker

  Name Contact
Prof. Dr. Mathias Jucker Prof. Dr. Mathias Jucker
Email:write Email
Tel.:+49 (0)7071 29 86863
www:website
Adr.:Dept. of Cellular Neurology
Hertie Institute for Clinical Brain Research
Otfried-Müller-Straße 27
 72076 Tübingen
 Germany
Area / Position CIN-Member
Department HIH Cellular Neurology, HIH and DZNE Tübingen
Scientific topic Brain Aging and Alzheimer's Disease
Field of research The research focus of the department is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases with a special focus on the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathies.
Methods Transgenic mouse models; in vivo multiphoton imaging; neuro-stereology
Publications
  1. Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret J, Paganetti P, Walsh DM, Mathews P, Ghiso J, Staufenbiel M, Walker L, Jucker M (2006) Exogenous induction of Afl-amyloidogenesis is governed by intrinsic properties of agent and host. Science. 313(5794):1781-4.
  2. Kaeser SA, Herzig MC, Coomaraswamy J, Kilger E, Selenica MLB, Winkler D, Staufenbiel M, Levy E, Grubb A, Jucker M (2007). Cystatin C modulates cerebral fl-amyloidosis. Nat Genet. 39(12):1437-9.
  3. Grathwohl SA, Kälin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, Jucker M (2009). Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat Neurosci. 2012(11):1361-3.
Keywords brain imaging; glia; neuro-immunology; neuro-pathology; neuro-plasticity; neurodegeneration
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News & Press
March 25 2015
Upcoming CIN Workshops

'Games of the Brain' series: Perception and Reasoning with S. Siegel


March 21 2015
Do-It-Yourself Neuroscience

Scientists of the University of Tübingen work internationally to offer research and training opportunities in the life sciences in developing countries, using 3D printing and affordable materials.

December 30 2014
Pointless Torture of Experimental Animals by Tübingen Neuroscientists?

Open letter by CIN chairman Peter Thier


December 13 2014
CIN Workshops: Games of the Brain Naturalizing Agency

Saturday, 13th December 2014 | 9.30am - 6.30pm | Hörsaal Forum Scientiarum (Doblerstr. 33, 72074 Tübingen)