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Prof. Dr. Mathias Jucker

  Name Contact
Prof. Dr. Mathias Jucker Prof. Dr. Mathias Jucker
Email:write Email
Tel.:+49 (0)7071 29 86863
www:website
Adr.:Dept. of Cellular Neurology
Hertie Institute for Clinical Brain Research
Otfried-Müller-Straße 27
 72076 Tübingen
 Germany
Area / Position CIN-Member
Department HIH Cellular Neurology, HIH and DZNE Tübingen
Scientific topic Brain Aging and Alzheimer's Disease
Field of research The research focus of the department is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases with a special focus on the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathies.
Methods Transgenic mouse models; in vivo multiphoton imaging; neuro-stereology
Publications
  1. Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret J, Paganetti P, Walsh DM, Mathews P, Ghiso J, Staufenbiel M, Walker L, Jucker M (2006) Exogenous induction of Afl-amyloidogenesis is governed by intrinsic properties of agent and host. Science. 313(5794):1781-4.
  2. Kaeser SA, Herzig MC, Coomaraswamy J, Kilger E, Selenica MLB, Winkler D, Staufenbiel M, Levy E, Grubb A, Jucker M (2007). Cystatin C modulates cerebral fl-amyloidosis. Nat Genet. 39(12):1437-9.
  3. Grathwohl SA, Kälin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, Jucker M (2009). Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat Neurosci. 2012(11):1361-3.
Keywords brain imaging; glia; neuro-immunology; neuro-pathology; neuro-plasticity; neurodegeneration
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News & Press
December 13 2014
CIN Workshops: Games of the Brain Naturalizing Agency

Saturday, 13th December 2014 | 9.30am - 6.30pm | Hörsaal Forum Scientiarum (Doblerstr. 33, 72074 Tübingen)


December 8 2014
New Publication in Nature Neuroscience

The retina changes its „language“ with changing brightness

A study at the University of Tübingen highlights the intricate nature
of visual responses - findings may help to improve digital cameras
as well as visual prosthetics