Prof. Dr. Mathias Jucker

  Name Contact
Prof. Dr. Mathias Jucker Prof. Dr. Mathias Jucker
Email:write Email
Tel.:+49 (0)7071 29 86863
www:website
Adr.:Dept. of Cellular Neurology
Hertie Institute for Clinical Brain Research
Otfried-Müller-Straße 27
 72076 Tübingen
 Germany
Area / Position CIN-Member
Department HIH Cellular Neurology, HIH and DZNE Tübingen
Scientific topic Brain Aging and Alzheimer's Disease
Field of research The research focus of the department is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases with a special focus on the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathies.
Methods Transgenic mouse models; in vivo multiphoton imaging; neuro-stereology
Publications
  1. Meyer-Luehmann M, Coomaraswamy J, Bolmont T, Kaeser S, Schaefer C, Kilger E, Neuenschwander A, Abramowski D, Frey P, Jaton AL, Vigouret J, Paganetti P, Walsh DM, Mathews P, Ghiso J, Staufenbiel M, Walker L, Jucker M (2006) Exogenous induction of Afl-amyloidogenesis is governed by intrinsic properties of agent and host. Science. 313(5794):1781-4.
  2. Kaeser SA, Herzig MC, Coomaraswamy J, Kilger E, Selenica MLB, Winkler D, Staufenbiel M, Levy E, Grubb A, Jucker M (2007). Cystatin C modulates cerebral fl-amyloidosis. Nat Genet. 39(12):1437-9.
  3. Grathwohl SA, Kälin RE, Bolmont T, Prokop S, Winkelmann G, Kaeser SA, Odenthal J, Radde R, Eldh T, Gandy S, Aguzzi A, Staufenbiel M, Mathews PM, Wolburg H, Heppner FL, Jucker M (2009). Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia. Nat Neurosci. 2012(11):1361-3.
Keywords brain imaging; glia; neuro-immunology; neuro-pathology; neuro-plasticity; neurodegeneration
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News & Press
April 14 2015
Tübinger Fenster für Forschung

The „Tübinger Fenster für Forschung“ (TÜFFF) on May 8th 2015 offers a glimpse of the top-level research performed in Tübingen - the CIN makes a showing with no less than eight booths.


April 13 2015
ACTION DIALOGUES | Public Lecture Series

The Public Lecture Series ACTION DIALOGUES brings together some of the leading figures of the major theoretical perspectives on action in Philosophy, Psychology, and Neuroscience.

March 25 2015
"Dem Gehirn beim Denken zusehen"

Scientists of the University of Tübingen decode mechanisms of associative learning in mice (press release in German).


March 21 2015
Do-It-Yourself Neuroscience

Scientists of the University of Tübingen work internationally to offer research and training opportunities in the life sciences in developing countries, using 3D printing and affordable materials.