Lecture: Special Lecture by Timothy J. Buschmann
Timothy J. Buschman, Massachusetts Institute of Technology (MIT), McGovern Institute for Brain Research:
'Neural Dynamics of Cognitive Control'
Cognitive control is the ability to direct behavior in a goal-directed manner. This ability lies at the core of intelligent behaviors, allowing us to focus our limited cognitive capacity on one task while still maintaining the flexibility to quickly switch to another task as the situation (or our goals) change. I will present results on the relative role of frontal and parietal cortices in two forms of cognitive control: the control of attention and flexible rule use. By leveraging large-scale, multiple-region electrophysiology in non-human primates I will highlight the importance of interactions within and between brain regions in supporting these cognitive functions. In particular, I will describe how these interactions can change rapidly to support different behaviors. One mechanism thought to underlie such flexible changes in inter-areal interactions is synchronization of neural activity, although how synchrony is established and modulated is not yet understood. Using electrophysiological and optogenetic techniques in mice I will begin to characterize the cell-type and frequency specificity of establishing and transferring synchrony within and between regions. Together, these results begin to build an understanding of the circuit- and network-level mechanisms underlying cognitive control.
- Werner Reichardt Centre for Integrative Neuroscience