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Prof. Dr. Nikos Logothetis

Organization: Max Planck Institute for Biological Cybernetics

Address:

Spemannstr. 38
72076 Tübingen
Germany

Phone number: +49 (0)7071 601 651

Department: Department of Physiology of Cognitive Processes

Area: CIN Members

Scientific topic: Systems Neuroscience


Field of Research

The aim of our research is to gain insights into the neural mechanisms of conscious perception, learning, categorization and recognition. We believe that research in systems neuroscience, today more than ever, requires more realistic working hypotheses regarding both the definition of the brain's elementary units of operation and the organization of these units in complex cortico-cortical and cortico-subcortico-cortical networks. Therefore, we study the elementary functional units in the cortex, microcircuits with balanced excitation-inhibition and global neural networks. Our very next aim is to examine the validity of our present results in other sensory systems, and -- most importantly -- in the context of behavior. In parallel we continue to develop and further improve technologies that will permit the implementation of an integrative approach to systems neuroscience questions, e.g., combined neuropharmacology-electrophysiology-fMRI experiments and development of paramagnetic tracers, just to name only two technologies.

Methods

We are using several methods and techniques in our department: functional MRI, also to guide multisite -- multielectrode recordings, combined electrophysiology-fMRI, neuropharmacology-electrophysiology-fMRI, high-resolution, diffusion, perfusion and parallel imaging, DTI, single voxel spectroscopy, chemical shift imaging, manganese-enhanced MRI (MEMRI), microstimulation, EEG, histology, capillary microsampling, LC-MS/MS and NMR.


Publications
  1. Leopold DA, Logothetis NK (1996). Activity Changes in Early Visual Cortex Reflect Monkeys' Percepts During Binocular Rivalry. Nature. 379(6565):549-53.
  2. Logothetis NK, Pauls J, Augath M, Trinath T, Oeltermann A (2001). Neurophysiological Investigation of the Basis of the fMRI Signal. Nature. 412(6843):150-57.
  3. Whittingstall K, Logothetis NK. Frequency-Band Coupling in Surface EEG Reflects Spiking Activity in Monkey Visual Cortex. Neuron. 64(2):281-9.