In 2007, the CIN started with 25 principal investigators as cluster applicants, as stipulated in the DFG call for bids. When the CIN cluster was approved further scientists from a range of institutions were incorporated, to make up the 48 'founding members' of the CIN. Since the beginning of 2014 the CIN has consisted of over 80 scientists in total. The membership process involves an application to the steering committee in which the candidate outlines his or her scientific profile and submits a list of publications. The committee's decision is based purely on the scientific excellence of each candidate.
Jun.-Prof. Dr. Vanessa Nieratschker
Organization: University Hospital Tübingen
Phone number: +49 7071 29 - 85523
Department: Molecular Psychiatry
Area: CIN Members
Scientific topic: Genetic and Epigenetic Basis of Psychiatric Disorders
Field of Research
My research group investigates the genetic and epigenetic basis of psychiatric disorders. Psychiatric disorders are complex disorders and various genetic, epigenetic as well as environmental factors contribute to their etiology. By researching the biological basis of these diseases, we are trying to better understand the origin and development of mental illnesses and contribute to the advancement of more effective therapeutic and preventive options.
Epigenetics, genetics, molecular research, addiction, early life stress
Brückmann C, Di Santo A, Karle K, Batra A, Nieratschker V. Validation of differential GDAP1 DNA methylation in alcohol dependence and its potential function as a biomarker for disease severity and therapy outcome. Epigenetics 2016 ; 11(6):456-63.
Nieratschker V, Brückmann C, Plewnia C. CACNA1C risk variant affects facial emotion recognition in healthy individuals. Scientific Reports 2015; 5:17349.
Nieratschker V, Kiefer C, Giel K, Krüger R, Plewnia C. The COMT Val/Met polymorphism modulates effects of tDCS on response inhibition. Brain stimulation 2015; 8(2):283-8.
Nieratschker V*, Massart R*, Gilles M*, Luoni A*, Suderman M, Krumm B, Meier S, Witt S, Nöthen M, Suomi S, Peus V, Scharnholz B, Dukal H, Hohmeyer C, Wolf I, Cirulli F, Gass P, Sütterlin M, Filsinger B, Laucht M, Riva M, Rietschel M, Deuschle M, Syzf M. MORC1 exhibits cross-species differential methylation in association with early life stress as well as genome-wide association with MDD. Translational psychiatry 2014; 4: e429.
Nieratschker V, Grosshans M, Frank J, Strohmaier J, von der Goltz C, El-Maarri O, Witt SH, Cichon S, Nothen MM, Kiefer F, Rietschel M. Epigenetic alteration of the dopamine transporter gene in alcohol-dependent patients is associated with age. Addiction biology 2014; 19(2): 305-311.
Nieratschker V, Lahtinen J, Meier S, Strohmaier J, Frank J, Heinrich A, Breuer R, Witt SH, Nothen MM, Rietschel M, Hovatta I. Longer telomere length in patients with schizophrenia. Schizophrenia research 2013; 149(1-3): 116-120.