Job Openings

PhD Studentship: The Role of Hippocampal Granule Cells in Memory Consolidation during Sleep

The information encoded by the brain during wakefulness in form of neural representations is reactivated during sleep, thus promoting its consolidation and long-term storage. While it was shown that repeated neural reactivations of hippocampal representations during sleep are essential for memory consolidation, it is not known whether and how do adult stem cells contribute to this process. Over recent years our laboratory has developed a modern toolkit enabling us to address this question (Kovalchuk et al., 2014, Liang et al., 2016).

Now we are looking for a motivated and talented PhD student interested in understanding how adult-born and mature granule cells in the hippocampal dentate gyrus contribute to memory consolidation during sleep. The student will team-up with other lab members and will learn/apply state‐of‐the art optical and electrophysiological techniques (in vivo two‐photon microscopy, the use of genetically-encoded calcium indicators, cell attached recordings, single cell electroporation, immunohistochemistry, etc.). The successful candidate can choose one of the two well structured training programs (Graduate school in Cellular & Molecular Neuroscience (http://www.neuroschool-tuebingen.de/master/cell-molec-neurosci) or PhD program in Experimental Medicine (https://www.medizin.uni-tuebingen.de/en/Research/Doctoral+Studies+at+the+MFT/PhD+Program+in+Experimental+Medicine.html).

Qualifications required: master’s degree in biology or medicine (ideally with focus on neuroscience). Previous laboratory experience in our research area (neuroscience, molecular biology, in vivo imaging) will be appreciated. In addition, candidates should be enthusiastic about learning new techniques and contributing to data collection and analysis. Good communication skills, ability to work in a team, and proficiency in English language are required.

Applications are welcome from overseas students as well as EU nationals. The application deadline is the 1st of December. The project starts in January 2018. Applications should include a detailed CV, a brief letter of motivation, and names of at least two reference persons. Please send these materials to Prof. Garaschuk (olga.garaschuk@uni-tuebingen.de). For further information about the lab please visit www.physiologie2.uni-tuebingen.de.

Find the job offer available for download here.


PhD and Postdoc Positions in Sensory/Systems Neuroscience

In January 2017, the collaborative research centre “Robust Vision – Inference Principles and Neural Mechanisms” (CRC 1233) started. Funded by the DFG (German Research Foundation), a group of more than 20 PIs will jointly address the question why biological visual systems are so remarkably robust. To this end, we will combine expertise in experimental and computational neuroscience, as well as in machine learning and computer vision.

As part of interdisciplinary collaborations within the CRC, 9 PhD and 2 Postdoc positions are available in different labs at the University of Tübingen.


Positions

1.   One PhD position is available in the group of Philipp Berens at the Institute for Ophthalmic Research and the Center for Integrative Neuroscience (CIN) of the University of Tübingen. In collaboration with Laura Busse (LGN/V1 physiology, LMU Munich) and Thomas Euler (retinal imaging, University of Tübingen), the project will investigate transformations of representations between the retina and the dorsolateral geniculate nucleus (dLGN) of the thalamus.

The student in the Berens lab will be responsible for data analysis and development of new models of neural processing in the retina and LGN. The project requires strong analytical skills and programming experience ideally in Python/R; a background in computational neuroscience or machine learning is considered a plus. A second PhD student based primarily in Munich will have an experimental focus. Because of the interdisciplinary nature of the project, excellent collaboration and team skills are essential.

Applications should include a CV, a statement of research motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to philipp.berensuni-tuebingen.de and add [CRC PhD Student] in the title. See also “General Information” below.


2.   One PhD position is available in the lab of Frank Schaeffel at the Ophthalmic Research Institute. The project studies perceptual consequences  of fixational eye movements and will be jointly supervised by Frank Schaeffel, Ziad Hafed at the CIN and Katharina Rifai at the Zeiss Vision Lab.

Profile of expertise is neurophysiology, vision, physiological  optics, human psychophysics, C++ programming (or at least strong interest in learning it). We are looking for a biologist, psychologist, or someone from related fields. Eligibility  for the PhD program is mandatory (a Master degree or equivalent).

Applications should include a statement of interest, CV, certificates documenting scientific training, two names for references, and a publication list. Please compile your application in one single PDF file and e-mail it to frank.schaeffeluni-tuebingen.de. See also “General Information” below.


3.   One Postdoc position is available in the lab of Ziad Hafed at the CIN. The research project represents a neurophysiological analysis of the visual consequences of fixational eye movements, using non-human primate neurophysiology and will be jointly supervised by Ziad Hafed, Frank Schaeffel and Katharina Rifai.

The profile of expected expertise includes visual system,  neurophysiology, C++ and/or MatLab programming (or at least strong interest in learning it). Experience with non-human primate neurophysiology is not mandatory (will be learned in the lab), but will be highly valued. We are looking for a biologist, psychologist, or somebody from related fields. Completed requirements for a PhD are mandatory.

Applications should include a statement of interest, CV, certificates documenting scientific training, two names for references, and a publication list. Please compile your application in one single PDF file and e-mail it to ziad.m.hafedcin.uni-tuebingen.de. See also “General Information” below.


4. One PhD position is available in the group of Günther Zeck at the Natural and Medical Sciences Institute (NMI) at the University of Tübingen.

In collaboration with Jakob Macke (caesar Bonn) , Katharina Stingl and Eberhart Zrenner (Ophthalmic Research Institute, University of Tübingen), the project “Image-processing computations in artificial vision“ will investigate how electrically stimulated blind retina will achieve robust object coding. The PhD student will be responsible for electrical stimulation and for extracellular recording from blind mouse retina using micro-electrode arrays. Together with the collaboration partners, algorithms for robust object identification will be developed and tested with blind patients.

The project requires skills in neural engineering, interest in neural computations and the readiness to acquire the necessary experimental skills. Because of the interdisciplinary nature of the project, excellent collaboration and team skills are essential.

Applications should include a CV, a statement of research motivation and experience, and the names of two referees. Please compile your application in one single PDF-file and email it to guenther.zecknmi.de and add [CRC PhD Student] in the title. See also “General Information” below.

5. Two PhD positions are available in the lab of Hendrikje Nienborg at the Centre for Integrative Neuroscience (CIN) as part of two collaborative projects.

The first project, a collaboration between Hendrikje Nienborg, Felix Wichmann and Jakob Macke (Research Center caesar Bonn), examines top-down control of sensory representations in the visual cortex for visual inference. It combines psychophysics in humans and nonhuman primates, machine learning, statistical modelling and multichannel extracellular recordings across layers in visual cortex. The PhD student will be responsible for the electrophysiological recordings and data analysis guided by statistical modelling in close interaction with a PhD student responsible for model development based in the Macke lab, and informed by human psychophysics performed in the Wichmann lab.
The position requires strong experimental and programming skills (ideally in Matlab or Python), and a background in neuroscience, computer science, electrical engineering, experimental psychology or a related field.

The second project is a collaboration between Hendrikje Nienborg and Karsten Rauss/Jan Born and examines sleep dependent signatures of perceptual learning. It combines high-density EEG recordings and fMRI in humans with wireless multichannel recordings in monkey visual cortex. The PhD student will be part of the team establishing the wireless recordings and responsible for the multichannel extracellular recordings and data analysis. The candidate will interact closely with a PhD based in the Born group responsible for the EEG and fMRI experiments in humans. The position requires strong engineering and experimental skills and a background in electrical engineering, computer science, neuroscience or a related field. Programming experience (ideally in Matlab or Python) will be highly valued.

Applications should include a CV, a brief statement of motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to hendrikje.nienborgcin.uni-tuebingen.de and add [CRC PhD Student] in the title. See also “General Information” below.

6. One Postdoc position and one PhD position are available in the lab of Markus Siegel at the Centre for Integrative Neuroscience (CIN) and MEG Center Tübingen.

Both positions will focus on an interdisciplinary project investigating large-scale neuronal interactions during natural vision. The project combines magnetoencephalography (MEG) recordings in humans with directly comparable EEG and large-scale extracellular multichannel recordings in non-human primates. The postdoc and PhD will both join an international and interdisciplinary team. Both will closely collaborate during the entire project. The positions require strong experimental and programming (ideally Matlab) skills, a keen interest in neurophysiology, and a background in neuroscience, biology, experimental psychology or related fields. Experience with human or animal electrophysiology will be highly valued.

Applications should include a CV, a brief statement of motivation and experience, and the names of at least two referees. Please compile your application in one single PDF-file and email it to markus.siegeluni-tuebingen.de. See also “General Information” below.


General information

For the PhD position applications, eligibility for the PhD program is mandatory (a MSc degree or equivalent). Positions are immediately available, with funding for 3 years (with the option on a 1-year extension). We offer employment with a salary and social benefits based on the collective agreement for public service employees in the academic and science sector, TV-L. The CRC promotes gender equality and therefore particularly encourages female scientists to apply. Preferential status will be given to handicapped persons, if equally qualified.

The Werner Reichardt Centre for Integrative Neuroscience (CIN) is an interdisciplinary institution funded by the German Excellence Initiative program. The CIN strives to deepen our understanding of how the brain generates function and how brain diseases impair functions. Its scientific program is guided by the conviction that progress in the understanding of brain function can be achieved with an integrative approach spanning multiple levels of organization and pooling the knowledge of researchers from many different fields.

The Institute for Ophthalmic Research cooperates closely with the University Eye Hospital under the umbrella of the Centre for Ophthalmology. The Institute aims at uncovering the causes for degenerative, inflammatory, neoplastic, and vascular diseases of the eye and developing diagnostics and therapies based on these discoveries. Translational research is jointly performed with the University Eye Hospital Tuebingen.

Tübingen is a vibrant university city in the south of Germany. Besides the CIN, Tübingen is also home to the Hertie Institute for Cognitive Neurology and several institutes of the Max Planck Society, among others. This allows for a tremendous exposure to the latest advances in neuroscience, vision/robotics, human-computer interaction, brain-computer interfaces, etc. There are also opportunities for collaborative projects across labs/institutes.


PhD Positions: Imaging Axonal Injury at a Nanoscale Level

Our newly established laboratory at the Centre for Integrative Neuroscience (CIN) in Tübingen is looking for

PhD Candidates

starting from autumn 2016 or later.

We are interested in mechanisms of axonal injury in neuroinflammatory diseases, such as multiple sclerosis (MS). Axonal injury in MS is a major cause of irreversible clinical deficits that patients develop. That is why the understanding of axonal damage is crucial for the development of new therapeutic strategies.

The selected candidate will look at the ultrastructural changes happening in damaged axons in mouse models of neuroinflammation and in vitro. S/he will combine cutting-edge super-resolution microscopy with modern chemical biology-based protein-engineering tools for live cell labeling. As this project has a tool development component, the successful candidate should be interested in and enthusiastic about method development as well. Previous experience with animal handling, microscopy, image processing or cell/molecular biology techniques is beneficial, but not necessary. The most important criteria for selection are motivation, curiosity, capability/wish to work in an international team, as well as good proficiency in English.

Applications should contain a brief statement of research experience and interests, CV, and names/contact details of 2-3 referees. Please direct your application or any informal enquiries by email to Ivana Nikić, head of research group. Applications should be sent electronically as a single PDF file.


PhD Position Dendritic Integration

The labs of Philipp Berens (www.berenslab.org) and Thomas Euler (www.eulerlab.de) at the Center for Integrative Neuroscience (CIN) at the Eberhard-Karls-University of Tübingen are offering a PhD position

(TV-L E13 65%)

to be filled as soon as possible, with funding for 3 years. We offer employment with a salary and social benefits based on the collective agreement for public service employees in the academic and science sector, TV-L. The Eberhard-Karls-University of Tübingen promotes gender equality and therefore particularly encourages female scientists to apply. Preferential status will be given to handicapped persons, if equally qualified.

The successful candidate will combine experimental and computational approaches to study neuronal cell type specific computations in the mouse retina. The goal of the project is to provide an account of how the functional response properties of selected ganglion cell types arise from their anatomical structure, connectivity and dendritic integration properties. We envision a highly interdisciplinary project, where the successful candidate will perform state- of-the-art optical imaging and electrophysiological recordings and use computational approaches to analyze their data.

The CIN offers a stimulating interdisciplinary scientific environment where research is carried out at all levels of neuroscience. The two labs are also part of the Institute for Ophthalmic Research (Eye Hospital Tübingen) and affiliated with the Bernstein Centre for Computational Neuroscience (BCCN).

Furthermore, the project will be performed in collaboration with the lab of Tom Baden at the University of Sussex, UK (www.badenlab.org).

Requirements:

  • Background in statistics, machine learning and data analysis
  • Experience with electrophysiology and/or two-photon imaging or a strong desire to learn these techniques
  • Programming experience in Python, Matlab, R or similar
  • Strong quantitative skills

 

Interested applicants should contact Dr. Philipp Berens (philipp.berens@uni-tuebingen.de) providing:

  • a curriculum vitae
  • a one-page description of past research experience & future research interests
  • a one-page description of the motivation for applying to this position
  • names of at least two people that could provide letters of reference

 

Please compile your application in one single PDF-file.

Click here to download the job offer as a PDF.


PhD Positions in Neural Circuits, Synaptic Physiology and Behaviour

The newly established Andrea Burgalossi laboratory at the Centre for Integrative Neuroscience (CIN) is looking for PhD and Postdoc candidates.

Our lab investigates the cellular and synaptic basis of behaviour. We employ state-of-the-art methods developed in the Brecht lab (Lee et al., 2009; Burgalossi et al., 2011) to record intracellularly and juxtacellularly from single neurons in freely behaving animals, in combination with anatomical, molecular and optogenetic techniques. We use rodents (mice/rats) as model system, and focus primarily on the mechanisms by which external space is represented in the mammalian cortex.

The successful candidate will explore the circuit structure and synaptic mechanisms involved in spatial cognitive behaviours, and more generally in learning and memory. The candidate will join a team of young and enthusiastic members in the dynamic scientific environment of CIN.

Applications should contain a brief statement of research experience and interests, CV, and names of at least two referees. Please direct your application or any informal inquiries to research group leader Dr. Andrea Burgalossi. Applications should be sent electronically as a single PDF file.

 


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